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Includes exclusive license outside U.S. for ompenaclid, an oral inhibitor of the creatine transport channel SLC6A8, and follow-on compounds.
January 4, 2024
By: Anthony Vecchione
Merck KGaA Darmstadt, Germany entered into a licensing agreement with Inspirna, Inc. for ompenaclid (RGX-202), a first-in-class oral inhibitor of the creatine transport channel SLC6A8, and SLC6A8-targeting follow-on compounds. Ompenaclid is currently being evaluated in a Phase II study for the second-line treatment of RAS-mutated (RASmut) advanced or metastatic colorectal cancer (mCRC). Merck KGaA will receive an exclusive license to ompenaclid outside of the U.S. and an option to co-develop ...
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